Article
The danger of "multi-tasking": LBR out of control.
Nucleus (Austin, Tex.) - 1 Jan 2000
Herrmann Harald, Zwerger Monika
Abstract excerpt
The nuclear envelope (NE) is a barrier that separates nuclear from cytoplasmic processes. It is composed of an inner and outer nuclear membrane (INM, ONM), separated by the perinuclear space (PNS). The ONM is contiguous with the endoplasmic reticulum (ER), and thus, the lumen of the NE and that of the ER constitute one compartment. The lamin B receptor (LBR) is a NE protein that has a central structural role as a...
Topics
- Cell Line
- Cell Line, Tumor
- Cell Nucleus
- Chromatin
- Endoplasmic Reticulum
- Gene Expression Profiling
- HeLa Cells
- Humans
- Mutation
- Nuclear Envelope
- Osteochondrodysplasias
- Pelger-Huet Anomaly
- Phenotype
- Receptors, Cytoplasmic and Nuclear
- Lamin B Receptor