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Article

Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization.

The Journal of cell biology - 30 Apr 2001

Schirmer E C, Guan T, Gerace L

Abstract excerpt

The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea. To investigate lamina functions, we have characterized a novel lamin B1 mutant lacking the middle approximately 4/5 of its alpha-helical rod domain. Though retaining...

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Identifiers

PMID: 11331300
DOI: 10.1083/jcb.153.3.479
PMCID: PMC2190570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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