Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers.

The American journal of gastroenterology - 1 Mar 2017

Drew David A, Nishihara Reiko, Lochhead Paul, Kuchiba Aya, Qian Zhi Rong, Mima Kosuke, Nosho Katsuhiko, Wu Kana, Wang Molin, Giovannucci Edward, Fuchs Charles S, Chan Andrew T, Ogino Shuji

Abstract excerpt

OBJECTIVES: Cigarette smoking has been linked to somatic genetic and epigenetic aberrations, including CpG island methylator phenotype (CIMP)-high, microsatellite instability (MSI)-high and BRAF mutation. These molecular features have been associated with synchronous primary colorectal cancers (CRCs). Thus, we examined the hypothesis that smoking might be associated with the risk of synchronous CRCs. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microsatellite Instability
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to Multivariate Analysis

Share to Neoplasms, Multiple Primary

Share to Proportional Hazards Models

Share to Proto-Oncogene Proteins B-raf

Share to Smoking Cessation

Source

Open in PubMed Open full text

Identifiers

PMID: 28117362
DOI: 10.1038/ajg.2016.589
PMCID: PMC5342916

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Prospective Study of Smoking and Risk of Synchronous Colorectal Cancers.PMID 28117362Read ↗

Association Between Smoking and Molecular Subtypes of Colorectal Cancer.Semantic proximity Read ↗

Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathwaysSemantic proximity Read ↗

A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.Semantic proximity Read ↗

Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk.Semantic proximity Read ↗

Smoking and risk of colorectal cancer according to KRAS and BRAF mutation status in a Japanese prospective Study.Semantic proximity Read ↗

Cigarette smoking and colorectal cancer risk by molecularly defined subtypes.Semantic proximity Read ↗

Clinicopathological and molecular features of colorectal cancer with synchronous adenoma.Semantic proximity Read ↗

Smoking and colorectal cancer in Lynch syndrome: results from the Colon Cancer Family Registry and the University of Texas M.D. Anderson Cancer Center.Semantic proximity Read ↗

Effects of interactions between common genetic variants and smoking on colorectal cancer.Semantic proximity Read ↗

Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype.Semantic proximity Read ↗

Smoking metabolic signature modifies the risk of colorectal cancer and interacts with genetic susceptibility: a large-scale prospective cohort study.Semantic proximity Read ↗

Clinicopathologic and molecular characteristics of synchronous colorectal cancers: heterogeneity of clinical outcome depending on microsatellite instability status of individual tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.