Article
Effects of interactions between common genetic variants and smoking on colorectal cancer.
BMC cancer - 19 Dec 2017
Song Nan, Shin Aesun, Jung Hye Soo, Oh Jae Hwan, Kim Jeongseon
Abstract excerpt
BACKGROUND: Although genome-wide association studies (GWAS) have identified variants in approximately 40 susceptibility loci for colorectal cancer (CRC), there are few studies on the interactions between identified single-nucleotide polymorphisms (SNPs) and lifestyle risk factors. We evaluated whether smoking could modify associations between these genetic variants and CRC risk. METHODS: A total of 703 CRC...
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