Article

gAIRR-wgs: An Algorithm to Genotype T Cell Receptor Alleles Using Whole Genome Sequencing Data

2025-10-13

Abstract excerpt

<h4>ABSTRACT</h4> T cell receptor ( TR ) genes, including variable (TR_V), diversity (TR_D), and joining (TR_J) segments, exhibit allelic diversity that is critical to adaptive immunity. Growing evidence has identified associations between TR genes and immune-related diseases. Germline variants may influence TR gene function and subsequent usage, highlighting the importance of accurate TR allele profiling. Ho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d57ea20c-a3a0-5ecf-b59a-55a323931057
DOI: 10.1101/2025.10.11.681280

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

gAIRR-wgs: An Algorithm to Genotype T Cell Receptor Alleles Using Whole Genome Sequencing DataDOI 10.1101/2025.10.11.681280Read

gAIRR-wgs: high-resolution T cell receptor allele typing in biobank-scale whole-genome sequencing data.Semantic proximity Read

Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR SuiteSemantic proximity Read

Unmasking Human T Cell Receptor Germline Diversity: 335 Novel Alleles Identified in 47 Pangenome Reference Individuals Using the gAIRR SuiteSemantic proximity Read

pmTR database: population matched (PM) germline allelic variants of T-cell receptor ( <i>TR</i> ) lociSemantic proximity Read

pmTR database: population matched (PM) germline allelic variants of T-cell receptor (TR) lociSemantic proximity Read

pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci.Semantic proximity Read

Genotyping of selected germline adaptive immune system loci using short-read sequencing data.Semantic proximity Read

Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta and beta lociSemantic proximity Read

Ultrasensitive allele inference from immune repertoire sequencing data with MiXCR.Semantic proximity Read

A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data.Semantic proximity Read

Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta, and beta lociSemantic proximity Read

Detecting T cell receptor rearrangements <i>in silico</i> from non-targeted DNA-sequencing (WGS/WES)Semantic proximity Read