Article
Adaptive immune receptor genotyping using the corecount program.
Frontiers in immunology - 1 Jan 2023
Narang Sanjana, Kaduk Mateusz, Chernyshev Mark, Karlsson Hedestam Gunilla B, Corcoran Martin M
Abstract excerpt
We present a new Rep-Seq analysis tool called corecount, for analyzing genotypic variation in immunoglobulin (IG) and T cell receptor (TCR) genes. corecount is highly efficient at identifying V alleles, including those that are infrequently used in expressed repertoires and those that contain 3' end variation that are otherwise refractory to reliable identification during germline inference from expressed...
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