Article
Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Arthritis & rheumatology (Hoboken, N.J.) - 1 May 2016
Lessard Christopher J, Sajuthi Satria, Zhao Jian, Kim Kwangwoo, Ice John A, Li He, Ainsworth Hannah, Rasmussen Astrid, Kelly Jennifer A, Marion Mindy, Bang So-Young, Joo Young Bin, Choi Jeongim, Lee Hye-Soon, Kang Young Mo, Suh Chang-Hee, Chung Won Tae, Lee Soo-Kon, Choe Jung-Yoon, Shim Seung Cheol, Oh Ji Hee, Kim Young Jin, Han Bok-Ghee, Shen Nan, Howe Hwee Siew, Wakeland Edward K, Li Quan-Zhen, Song Yeong Wook, Gaffney Patrick M, Alarcón-Riquelme Marta E, Criswell Lindsey A, Jacob Chaim O, Kimberly Robert P, Vyse Timothy J, Harley John B, Sivils Kathy L, Bae Sang-Cheol, Langefeld Carl D, Tsao Betty P
Abstract excerpt
OBJECTIVE: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder whose etiology is incompletely understood, but likely involves environmental triggers in genetically susceptible individuals. Using an unbiased genome-wide association (GWA) scan and replication analysis, we sought to identify the genetic loci associated with SLE in a Korean population. METHODS: A total of 1,174 SLE cases and 4,246...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
