Article
Octopamine enhances oxidative stress resistance through the fasting-responsive transcription factor DAF-16/FOXO in C. elegans.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2017
Hoshikawa Haruka, Uno Masaharu, Honjoh Sakiko, Nishida Eisuke
Abstract excerpt
Dietary restriction regimens lead to enhanced stress resistance and extended life span in many species through the regulation of fasting and/or diet-responsive mechanisms. The fasting stimulus is perceived by sensory neurons and causes behavioral and metabolic adaptations. Octopamine (OA), one of the Caenorhabditis elegans neurotransmitters, is involved in behavioral adaptations, and its levels are increased...
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