Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway.

Experimental gerontology - 1 May 2013

Wan Qin-Li, Zheng Shan-Qing, Wu Gui-Sheng, Luo Huai-Rong

Abstract excerpt

Aspirin has been revealed to have many beneficial effects for health since it was discovered as a nonsteroidal anti-inflammatory drug (NSAID) to treat pain and inflammation. Here, we investigated the molecular mechanism of aspirin on the lifespan extension of Caenorhabditis elegans. Our results s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinase Kinases
Share to Aspirin
Share to Drug Evaluation, Preclinical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electron Transport Complex III

Share to Food Deprivation

Share to Movement

Share to Receptors, Nicotinic

Share to Telomere-Binding Proteins

Source

Identifiers

PMID: 23485446
DOI: 10.1016/j.exger.2013.02.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23485446-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway.PMID 23485446Read ↗

Aspirin increases metabolism through germline signalling to extend the lifespan of Caenorhabditis elegans.Semantic proximity Read ↗

Gastrodin extends the lifespan of Caenorhabditis elegans via the DAF-16/FOXO signaling pathway and autophagySemantic proximity Read ↗

Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way.Semantic proximity Read ↗

Raspberry extract promoted longevity and stress tolerance via the insulin/IGF signaling pathway and DAF-16 in Caenorhabditis elegansSemantic proximity Read ↗

A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response.Semantic proximity Read ↗

Caenorhabditis elegans as a Useful Model for Studying Aging Mutations.Semantic proximity Read ↗

Gengnianchun Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF-1 Signalling Pathway.Semantic proximity Read ↗

Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age‐Related Diseases by Activating AMPK, DAF‐16, and HSF‐1Semantic proximity Read ↗

Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF‐16/FOXO‐ and SKN‐1/NRF2‐Related Signaling PathwaysSemantic proximity Read ↗

Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans.Semantic proximity Read ↗

Secoisolariciresinol Diglucoside Delays the Progression of Aging-Related Diseases and Extends the Lifespan ofCaenorhabditis elegansvia DAF-16 and HSF-1Semantic proximity Read ↗

Tipepidine extends median lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.