Article
Short report: codon 125 polymorphism of CD31 and susceptibility to malaria.
The American journal of tropical medicine and hygiene - 1 Dec 2001
Casals-Pascual C, Allen S, Allen A, Kai O, Lowe B, Pain A, Roberts D J
Abstract excerpt
Platelet-endothelial cell adhesion molecule 1 (PECAM-1/CD31) has been identified as an endothelial cell receptor of Plasmodium falciparum-infected erythrocytes. The significance of adhesion of infected erythrocytes to this receptor in malaria infection has not been determined. We have therefore studied the association of the functional mutation CTG-->GTG (Leu-->Val) in codon 125 of the Cd31 gene with severe...
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