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Article

Fibronectin-guided migration of carcinoma collectives

19 Jan 2017

Abstract excerpt

Functional interplay between tumour cells and their neoplastic extracellular matrix plays a decisive role in malignant progression of carcinomas. Here we provide a comprehensive data set of the human HNSCC-associated fibroblast matrisome. Although much attention has been paid to the deposit of collagen, we identify oncofetal fibronectin (FN) as a major and obligate component of the matrix assembled by stromal...

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PMID: 28102238
DOI: 10.1038/ncomms14105

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