Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Leader Position of Mesenchymal Cells Expressing N-Cadherin in the Collective Migration of Epithelial Cancer

16 Mar 2020

Abstract excerpt

Understanding how heterogeneous cancer cell populations migrate collectively is of paramount importance to arrest metastasis. Here, we applied 3D culture-based approaches for in vitro modeling of the collective migration of squamous carcinoma cells and examine the impact of epithelial and mesenchymal cell interactions on this type of migration. We show that both mesenchymal N-cadherin-expressing cancer cells and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32188112
DOI: 10.3390/cells9030731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Leader Position of Mesenchymal Cells Expressing N-Cadherin in the Collective Migration of Epithelial CancerPMID 32188112Read ↗

Mechanisms of Motility in Metastasizing CellsSemantic proximity Read ↗

Post-EMT: Cadherin-11 mediates cancer hijacking fibroblastsSemantic proximity Read ↗

Fibronectin-guided migration of carcinoma collectivesSemantic proximity Read ↗

Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model.Semantic proximity Read ↗

A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migrationSemantic proximity Read ↗

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancerSemantic proximity Read ↗

Collective cell migration: Implications for wound healing and cancer invasionSemantic proximity Read ↗

A biophysical model of Epithelial-Mesenchymal Transition uncovers the frequency and size distribution of Circulating Tumor Cell clusters across cancer typesSemantic proximity Read ↗

Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer MigrationSemantic proximity Read ↗

Leader Cells: Invade and Evade—The Frontline of Cancer ProgressionSemantic proximity Read ↗

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancerSemantic proximity Read ↗

Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell matrix interaction in 3DSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.