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TGFβ, Fibronectin and Integrin α5β1 Promote Invasion in Basal Cell Carcinoma

15 Jul 2018

Abstract excerpt

Basal cell carcinoma (BCC) is the most frequent human cancer and is becoming an important health problem in an aging population. Based on their clinical and histological characteristics, thick BCC are typically divided into low-risk nodular and high-risk infiltrative subtypes, although the underlying mechanisms are poorly understood. We have identified molecular mechanisms that explain the aggressiveness of...

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PMID: 29758283
DOI: 10.1016/j.jid.2018.04.029

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