Article
The gender-specific association of rs334558 in GSK3β with major depressive disorder.
Medicine - 1 Jan 2017
Liu Sha, Wang Le, Sun Ning, Yang Chunxia, Liu Zhifen, Li Xinrong, Cao Xiaohua, Xu Yong, Zhang Kerang
Abstract excerpt
Major depressive disorder (MDD) is one of the most prevalent psychiatric illnesses with a heritability ranging from 40% to 50%. The single nucleotide polymorphism (SNP) rs334558 on the glycogen synthase kinase-3β (GSK3β) gene has been identified as a genetic risk loci associated with schizophrenia and bipolar disorder. However, results from replication studies examining the association between rs334558 and MDD...
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