Article
[Association study between Protein Kinase C gamma gene polymorphism and major depressive disorder].
Zhonghua yi xue za zhi - 23 Mar 2010
Wang Xuan, Sun Yan, Sun Ning, Liu Wei, Lang Xiao-e, Yang Rong, Wu Chang-sheng, Zhang Ke-rang
Abstract excerpt
OBJECTIVE: To explore the genetic association of PKCgamma gene rs3745406 polymorphism with major depressive disorder (MDD) and their clinical phenotypes. METHODS: A total of 453 Chinese Han MDD patients with an initial episode were recruited from our hospital. The symptomatic phenotypes of these cases were evaluated by HAMD. Polymerase chain reaction (PCR) and direct sequencing analysis were used to detect the...
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