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The Gender-Specific Interaction of DVL3 and GSK3β Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study.

Oxidative medicine and cellular longevity - 1 Jan 2022

Ke Siyuan, Li Jiarui, Zhao Lu, Yang Jiarun, Zhao Xueyan, Zhang Wenxin, Qiu Xiaohui, Yang Xiuxian, Zhou Jiawei, Tong Yuying, Zhu Xiongzhao, Liu Xuan, Yang Yanjie, Qiao Zhengxue, Bu Tianyi

Abstract excerpt

Based on the "oxidative stress hypothesis" of major depressive disorder (MDD), cells regulate their structure through the Wnt pathway. Little is known regarding the interactions of dishevelled 3 (DVL3) and glycogen synthase kinase 3 beta (GSK3β) polymorphisms with MDD. The aim of the current study was to verify the relationship between DVL3 and GSK3β genetic variants in a Chinese Han population and further to...

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Identifiers

PMID: 35126809
DOI: 10.1155/2022/2633127
PMCID: PMC8816570

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