Downregulation of microRNA‑34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats.

doi:10.3892/mmr.2017.6122

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Article

Downregulation of microRNA‑34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats.

Molecular medicine reports - 1 Mar 2017

Yang Fan, Li Haiyu, Du Youyou, Shi Qiangwei, Zhao Luosha

Abstract excerpt

The present study aimed to identify the microRNA (miRNA) responsible for the development of primary hypertension, and examine the downstream signaling pathway, which mediates the effect of the miRNA. Reverse transcription‑quantitative polymerase chain reaction analysis was performed to identify which miRNA may be involved in the pathogenesis of hypertension. In silico analysis and a luciferase assay were used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28098882
DOI: 10.3892/mmr.2017.6122
PMCID: PMC5367366

Genes

CDK6
CCNG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.