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Article

MicroRNA‐494 inhibits the growth and angiogenesis‐regulating potential of mesenchymal stem cells

7 Feb 2015

Abstract excerpt

Mesenchymal stem cells (MSCs) play an important role in the pathology of preeclampsia (PE). Our previous microarray analysis found that microRNA-494 (miR-494) is highly expressed in decidua-derived MSCs (dMSCs) from PE. We hypothesized that aberrant expression of miR-494 in dMSCs is involved in PE development. In the present study, we found that miR-494 arrests G1/S transition in dMSCs by targeting CDK6 and...

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PMID: 25660325
DOI: 10.1016/j.febslet.2015.01.038

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