Article
MicroRNA-1246 regulates proliferation, invasion, and differentiation in human vascular smooth muscle cells by targeting cystic fibrosis transmembrane conductance regulator (CFTR).
Pflugers Archiv : European journal of physiology - 1 Feb 2021
Pan Diguang, Liu Guiyong, Li Bin, Jiang Jingbo, Chen Wei, Li Wei, Zhang Lin, Hu Yubao, Xie Shuyun, Yang Huayun
Abstract excerpt
MicroRNA (miRNA) plays a key role in the proliferation and invasion of vascular smooth muscle cells (VSMCs). However, the role and underlying mechanism of miRNAs in VSMCs are not fully understood. Therefore, this study was designed to investigate the role and mechanism of microRNA-1246 (miR-1246) in VSMCs. VSMCs were cultured, and the proliferation of VSMCs was stimulated by platelet-derived growth factor...
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