Article
Joint association of complement component 3 and CC-cytokine ligand2 (CCL2) or complement component 3 and CFH polymorphisms in age-related macular degeneration.
Ophthalmic genetics - 1 Jan 2000
Bonyadi Mortaza, Jabbarpoor Bonyadi Mohammad Hossein, Yaseri Mehdi, Mohammadian Tahereh, Fotouhi Nikou, Javadzadeh Alireza, Soheilian Masoud
Abstract excerpt
BACKGROUND: To determine the joint effect of complement component 3(C3 R102G) with CC-cytokine ligand2 (CCL2-2518) or complement factor H (CFH) Y402H polymorphisms on advanced age-related macular degeneration (AMD). METHODS: In this case-control study, 233 patients with advanced AMD and 159 unrelated healthy controls enrolled for evaluation. Selected polymorphisms were determined by polymerase chain reaction and...
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