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Article

Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels.

PloS one - 1 Jan 2014

Ristau Tina, Paun Constantin, Ersoy Lebriz, Hahn Moritz, Lechanteur Yara, Hoyng Carel, de Jong Eiko K, Daha Mohamed R, Kirchhof Bernd, den Hollander Anneke I, Fauser Sascha

Abstract excerpt

Age-related macular degeneration (AMD) is a common condition that leads to severe vision loss and dysregulation of the complement system is thought to be associated with the disease. To investigate associations of polymorphisms in AMD susceptibility genes with systemic complement activation, 2655 individuals were genotyped for 32 single nucleotide polymorphisms (SNPs) in or near 23 AMD associated risk genes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24675670
DOI: 10.1371/journal.pone.0093459
PMCID: PMC3968152

Genes

CFB
CFH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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