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Article

Association of combined complement factor H Y402H and ARMS2/LOC387715 A69S polymorphisms with age-related macular degeneration: an updated meta-analysis.

Ophthalmic genetics - 1 Aug 2020

Jabbarpoor Bonyadi Mohammad Hossein, Yaseri Mehdi, Soheilian Masoud

Abstract excerpt

BACKGROUND: Complement factor H (CFH) Y402 H (rs1061170) and age-related maculopathy susceptibility2 (ARMS2)/LOC387715 A69 S (rs10490924) polymorphisms shown to have significant association with AMD. In this meta-analysis, we updated and pooled the results of available association studies between combined ARMS2/LOC387715A69 S-CFHY402 H genotypes and AMD to estimate the synergistic effects. METHODS: Heterogeneity...

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PMID: 32406777
DOI: 10.1080/13816810.2020.1765396

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