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Article

Interactions among different genetic loci in age-related macular degeneration.

Ophthalmic genetics - 1 Apr 2018

Bonyadi Mortaza, Jabbarpoor Bonyadi Mohammad Hossein, Yaseri Mehdi, Soheilian Masoud

Abstract excerpt

PURPOSE: To evaluate the possible synergistic effect of at risk genotypes of ARMS2/LOC387715 (A69S), DNA repair SMUG1 rs3087404, CCL2-2518, C3 (R102G), CFH Y402H, complement factor B (L9H), and complement factor I (CFI) (G119R) in advanced age-related macular degeneration compared to those of healthy controls. Elucidation of synergistic effects between different genetic loci may clarify their pathogenetic...

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Source

Identifiers

PMID: 29087762
DOI: 10.1080/13816810.2017.1393829

Genes

CFH
ARMS2
CFI
CCL2
SMUG1

Variants

rs3087404
rs3087404
rs3087404
rs3087404
rs3087404

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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