Article
Evaluation of CC-cytokine ligand 2 and complementary factor H Y402H polymorphisms and their interactional association with age-related macular degeneration.
Acta ophthalmologica - 1 Dec 2016
Bonyadi Mortaza, Foruzandeh Zahra, Mohammadian Tahereh, Fotouhi Nikou, Soheilian Masoud, Jabbarpoor Bonyadi Mohammad Hossein, Javadzadeh Alireza, Moein Hamidreza, Yaseri Mehdi
Abstract excerpt
PURPOSE: To evaluate the association of CC-cytokine ligand 2 CCL2-2518 (rs1024611) single nucleotide polymorphism, complement factor H (CFH Y402H) and their possible interaction in developing advanced age-related macular degeneration (AMD). METHODS: In this case-control study, DNA samples from 266 patients with advanced AMD and 229 healthy controls were genotyped for CCL2 polymorphism and also 254 patients and...
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