Article

Longitudinal in vivo PET imaging of P2X7R and TSPO neuroinflammation markers and myelin load in the TgF344-AD rat model of Alzheimer’s disease

2025-07-23

Abstract excerpt

<title>Abstract</title> <bold>Background: </bold>Neuroinflammation and myelin loss are hallmark features of Alzheimer’s disease (AD) associated with cognitive decline. Emerging evidence highlights the significant role of glial cell activation, particularly microglia, in driving neuroinflammation and disease progression. While translocator protein (TSPO) PET imaging is commonly used to detect neuroinflammation,...

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Literature Corpus work: 15352cc7-b68a-5cbd-94b2-ae5fbc2924b7
DOI: 10.21203/rs.3.rs-7072571/v1

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