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Article

Giant cell tumor of soft tissue is genetically distinct from its bone counterpart.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2017

Lee Jen-Chieh, Liang Cher-Wei, Fletcher Christopher Dm

Abstract excerpt

Giant cell tumors of bone are locally aggressive bone neoplasms with a predilection for young adults. Histologically, they are composed of histiocytoid to spindled mononuclear cells, admixed with numerous large osteoclastic giant cells. Giant cell tumors of soft tissue are rare tumors that bear striking histological resemblance to giant cell tumors of bone and might be regarded as a soft tissue analog thereof....

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PMID: 28084336
DOI: 10.1038/modpathol.2016.236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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