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Article

Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.

Cardiovascular research - 1 Feb 2017

Meissner Anja, Miro Francesc, Jiménez-Altayó Francesc, Jurado Andrés, Vila Elisabet, Planas Anna M

Abstract excerpt

AIMS: Hypertension is a complex condition involving functional and structural alterations of the microvasculature and an activation of the immune system. T-lymphocytes play a crucial role during the development of hypertension in experimental models, yet the underlying mechanisms remain elusive. Lymphocyte egress from lymph nodes is controlled by sphingosine-1-phosphate (S1P), a natural lipid mediator regulating...

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Identifiers

PMID: 28082452
DOI: 10.1093/cvr/cvw256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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