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Article

S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling.

Mediators of inflammation - 1 Jan 2017

Kumar Ashok, Zamora-Pineda Jesus, Degagné Emilie, Saba Julie D

Abstract excerpt

Sphingosine-1-phosphate (S1P) is a potent lipid signaling molecule that regulates pleiotropic biological functions including cell migration, survival, angiogenesis, immune cell trafficking, inflammation, and carcinogenesis. It acts as a ligand for a family of cell surface receptors. S1P concentrations are high in blood and lymph but low in tissues, especially the thymus and lymphoid organs. S1P chemotactic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29333002
DOI: 10.1155/2017/7685142
PMCID: PMC5733215

Genes

SGPL1

Provenance

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