Article
Genetics of the ceramide/sphingosine-1-phosphate rheostat in blood pressure regulation and hypertension.
BMC genetics - 13 May 2011
Fenger Mogens, Linneberg Allan, Jørgensen Torben, Madsbad Sten, Søbye Karen, Eugen-Olsen Jesper, Jeppesen Jørgen
Abstract excerpt
BACKGROUND: Several attempts to decipher the genetics of hypertension of unknown causes have been made including large-scale genome-wide association analysis (GWA), but only a few genes have been identified. Unsolved heterogeneity of the regulation of blood pressure and the shortcomings of the prevailing monogenic approach to capture genetic effects in a polygenic condition are the main reasons for the modest...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.