Article
Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Jan 2017
Sabeva Nadezhda, Cho Richard W, Vasin Alexander, Gonzalez Agustin, Littleton J Troy, Bykhovskaia Maria
Abstract excerpt
Synaptic vesicles fuse at morphological specializations in the presynaptic terminal termed active zones (AZs). Vesicle fusion can occur spontaneously or in response to an action potential. Following fusion, vesicles are retrieved and recycled within nerve terminals. It is still unclear whether vesicles that fuse spontaneously or following evoked release share similar recycling mechanisms. Genetic deletion of the...
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