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Article

Presynaptic calcium channel localization and calcium-dependent synaptic vesicle exocytosis regulated by the Fuseless protein.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Apr 2008

Long A Ashleigh, Kim Eunju, Leung Hung-Tat, Woodruff Elvin, An Lingling, Doerge R W, Pak William L, Broadie Kendal

Abstract excerpt

A systematic forward genetic Drosophila screen for electroretinogram mutants lacking synaptic transients identified the fuseless (fusl) gene, which encodes a predicted eight-pass transmembrane protein in the presynaptic membrane. Null fusl mutants display >75% reduction in evoked synaptic transmission but, conversely, an approximately threefold increase in the frequency and amplitude of spontaneous synaptic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18385325
DOI: 10.1523/JNEUROSCI.5553-07.2008
PMCID: PMC2769928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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