Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release.

The Journal of cell biology - 12 May 2003

Wucherpfennig Tanja, Wilsch-Bräuninger Michaela, González-Gaitán Marcos

Abstract excerpt

During constitutive endocytosis, internalized membrane traffics through endosomal compartments. At synapses, endocytosis of vesicular membrane is temporally coupled to action potential-induced exocytosis of synaptic vesicles. Endocytosed membrane may immediately be reused for a new round of neurotransmitter release without trafficking through an endosomal compartment. Using GFP-tagged endosomal markers, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Compartmentation
Share to Exocytosis
Share to Membrane Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurotransmitter Agents

Share to Paralysis

Share to rab5 GTP-Binding Proteins

Share to Synaptic Membranes

Share to Synaptic Vesicles

Source

Open in PubMed Open full text

Identifiers

PMID: 12743108
DOI: 10.1083/jcb.200211087
PMCID: PMC2172938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release.PMID 12743108Read ↗

An essential role of Rab5 in uniformity of synaptic vesicle size.Semantic proximity Read ↗

Genetic and molecular analysis of synaptic vesicle recycling in Drosophila.Semantic proximity Read ↗

Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans.Semantic proximity Read ↗

Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins.Semantic proximity Read ↗

Complexin Mutants Reveal Partial Segregation between Recycling Pathways That Drive Evoked and Spontaneous Neurotransmission.Semantic proximity Read ↗

Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release.Semantic proximity Read ↗

Endocytosis in Drosophila: progress, possibilities, prognostications.Semantic proximity Read ↗

Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release.Semantic proximity Read ↗

Ca2+ influx through distinct routes controls exocytosis and endocytosis at drosophila presynaptic terminals.Semantic proximity Read ↗

AP180 maintains the distribution of synaptic and vesicle proteins in the nerve terminal and indirectly regulates the efficacy of Ca2+-triggered exocytosis.Semantic proximity Read ↗

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions.Semantic proximity Read ↗

Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.