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Article

Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression.

American journal of physiology. Renal physiology - 1 Apr 2017

Streets Andrew J, Magayr Tajdida A, Huang Linghong, Vergoz Laura, Rossetti Sandro, Simms Roslyn J, Harris Peter C, Peters Dorien J M, Ong Albert C M

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is the fourth most common cause of end-stage renal disease. The disease course can be highly variable and treatment options are limited. To identify new therapeutic targets and prognostic biomarkers of disease, we conducted parallel discovery microarray profiling in normal and diseased human PKD1 cystic kidney cells. A total of 1,515 genes and 5 miRNA were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28077374
DOI: 10.1152/ajprenal.00607.2016
PMCID: PMC5504395

Genes

EGF
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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