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Article

NS398 as a potential drug for autosomal-dominant polycystic kidney disease: Analysis using bioinformatics, and zebrafish and mouse models.

Journal of cellular and molecular medicine - 1 Oct 2021

Chen Sixiu, Huang Linxi, Zhou Shoulian, Zhang Qingzhou, Ruan Mengna, Fu Lili, Yang Bo, Xu Dechao, Mei Changlin, Mao Zhiguo

Abstract excerpt

Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by uncontrolled renal cyst formation, and few treatment options are available. There are many parallels between ADPKD and clear-cell renal cell carcinoma (ccRCC); however, few studies have addressed the mechanisms linking them. In this study, we aimed to investigate their convergences and divergences based on bioinformatics and explore the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Metabolic Networks and Pathways

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Identifiers

PMID: 34551202
DOI: 10.1111/jcmm.16903
PMCID: PMC8505825

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