Article
Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses.
Experimental gerontology - 1 Mar 2017
Christoffersen Mette, Frikke-Schmidt Ruth, Nordestgaard Børge G, Tybjærg-Hansen Anne
Abstract excerpt
BACKGROUND: Werner syndrome, a premature genetic aging syndrome, shares many clinical features reminiscent of normal physiological aging, and ischemic vascular disease is a frequent cause of death. We tested the hypothesis that genetic variation in the WRN gene was associated with risk of ischemic vascular disease in the general population. METHODS: We included 58,284 participants from two general population...
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