Article
The Werner syndrome gene and global sequence variation.
Genomics - 1 Jan 2001
Passarino G, Shen P, Van Kirk J B, Lin A A, De Benedictis G, Cavalli Sforza L L, Oefner P J, Underhill P A
Abstract excerpt
We have identified a dense set of markers useful in association studies involving the Werner syndrome (WRN) gene. The homozygotic disruption of the WRN gene is the cause of Werner disease. In addition, this gene is likely to be involved in many complex traits, such as aging, or at least some of the traits and diseases related to age. To investigate the genetic variation associated with the WRN gene, a sample of...
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