Article
Two novel susceptibility SNPs for ischemic stroke using exome sequencing in Chinese Han population.
Molecular neurobiology - 1 Apr 2014
Zhang Yanwei, Tong Yeqing, Zhang Yong, Ding Hu, Zhang Hao, Geng Yijie, Zhang Renli, Ke Yuebin, Han Jingjun, Yan Zhixiang, Zhou Li, Wu Tangchun, Hu Frank B, Wang Daowen, Cheng Jinquan
Abstract excerpt
Genome-wide association studies (GWAS) of ischemic stroke (IS) have been performed on several cohorts of Caucasian or African population and Japanese, resulting in somewhat inconsistent conclusion. We aimed to identify susceptibility loci for IS by exome sequencing in a Chinese Han population. Exome sequencing was used to screen susceptibility loci among 100 cases and 100 matched controls. Significant SNPs from...
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