Article
A polymorphic marker in the first intron of the Werner gene associates with cognitive function in aged Danish twins.
Experimental gerontology - 1 Jul 2004
Bendixen Mette H, Nexø Bjørn A, Bohr Vilhelm A, Frederiksen Henrik, McGue Matt, Kølvraa Steen, Christensen Kaare
Abstract excerpt
Werner's syndrome is a premature aging syndrome with many features common to normal aging. The possible association between phenotypic markers for normal aging and SNP's in the WRN gene was investigated in 426 dizygotic, Danish twins age 70-90 years. All participants were scored every second year using a number of physical and cognitive tests. In addition their self-rated health was registered as well as self...
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