Article
Unusual Microsatellite-Instable Mixed Neuroendocrine and Non-neuroendocrine Neoplasm: A Clinicopathological Inspection and Literature Review.
Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000
Pereira Daniela, White Daley, Mortellaro Michael, Jiang Kun
Abstract excerpt
BACKGROUND: Mixed neuroendocrine and non-endocrine neoplasms (MiNENs) are challenging to diagnose and manage clinically. The current understanding of MiNENs' pathobiology, molecular mechanisms, and management is incomplete. Though microsatellite instability (MSI) is known to impact carcinogenesis, reports examining MSI mechanisms for MiNENs are rare. METHODS: We report an unusual colonic MSI-MiNEN uncovered in an...
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