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Article

Colorectal neuroendocrine carcinomas and adenocarcinomas share oncogenic pathways. A clinico-pathologic study of 12 cases.

European journal of gastroenterology & hepatology - 1 Dec 2012

Karkouche Raymond, Bachet Jean-Baptiste, Sandrini Jeremy, Mitry Emmanuel, Penna Christophe, Côté Jean-François, Blons Hélène, Penault-Llorca Frédérique, Rougier Philippe, Saint André Jean-Paul, Emile Jean-François

Abstract excerpt

OBJECTIVE: Neuroendocrine carcinomas (NECs) are rare neoplasms with an increasing incidence. Oncogenetic pathways of colorectal NEC are still poorly understood, and no treatment standards are available for these rare tumors. METHODS: We analyzed retrospectively the clinical records and histology of 12 patients with colorectal NEC. KRAS and BRAF mutations were investigated after the dissection of exoendocrine and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23114745
DOI: 10.1097/MEG.0b013e3283583c87

Genes

KRAS
BRAF
ALK
EML4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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