Article
The Functional Haplotypes of CHRM3 Modulate mRNA Expression and Associate with Bladder Cancer among a Chinese Han Population in Kaohsiung City.
BioMed research international - 1 Jan 2016
Wang Chiang-Ting, Chen Tsung-Ming, Mei Chien-Tai, Chang Chun-Feng, Liu Li-Lian, Chiu Kuo-Hsun, Wu Tsung-Meng, Lan Yu-Ching, Liu Wen-Sheng, Chen Ya-Huey, Lin Yi-Mei Joy
Abstract excerpt
Bladder cancer is one of the major cancer types and both environmental factors and genetic background play important roles in its pathology. Kaohsiung is a high industrialized city in Taiwan, and here we focused on this region to evaluate the genetic effects on bladder cancer. Muscarinic acetylcholine receptor M3 (CHRM3) was reported as a key receptor in different cancer types. CHRM3 is located at 1q42-43 which...
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