Article
Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population.
Scientific reports - 28 Apr 2016
Ke Juntao, Lou Jiao, Zhong Rong, Chen Xueqin, Li Jiaoyuan, Liu Cheng, Gong Yajie, Yang Yang, Zhu Ying, Zhang Yi, Chang Jiang, Gong Jing
Abstract excerpt
Genome-wide association studies (GWAS) have established chromosome 3p21.31 as a susceptibility locus for colorectal cancer (CRC) that lacks replication and exploration in the Chinese population. We searched potentially functional single nucleotide polymorphisms (SNPs) in the linkage disequilibrium (LD) block of 3p21.31 with chromatin immunoprecipitation-sequencing (ChIP-seq) data of histone modification, and...
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