Article
Myeloid-derived suppressor cells in cancer: therapeutic, predictive, and prognostic implications.
Seminars in oncology - 1 Apr 2014
Diaz-Montero C Marcela, Finke Jim, Montero Alberto J
Abstract excerpt
Immune evasion is a hallmark of cancer. While there are multiple different mechanisms that cancer cells employ, myeloid-derived suppressor cells (MDSCs) are one of the key drivers of tumor-mediated immune evasion. MDSCs begin as myeloid cells recruited to the tumor microenvironment, where they ar...
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