Article
Assessment of Common and Emerging Bioinformatics Pipelines for Targeted Metagenomics.
PloS one - 1 Jan 2017
Siegwald Léa, Touzet Hélène, Lemoine Yves, Hot David, Audebert Christophe, Caboche Ségolène
Abstract excerpt
Targeted metagenomics, also known as metagenetics, is a high-throughput sequencing application focusing on a nucleotide target in a microbiome to describe its taxonomic content. A wide range of bioinformatics pipelines are available to analyze sequencing outputs, and the choice of an appropriate tool is crucial and not trivial. No standard evaluation method exists for estimating the accuracy of a pipeline for...
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