Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Validation of a next generation sequencing panel for detection of hotspot cancer mutations in a clinical laboratory.

Pathology, research and practice - 1 Feb 2017

Shahsiah Reza, DeKoning Jenefer, Samie Saeed, Latifzadeh Seyed Ziaeddin, Kashi Zahra Mehdizadeh

Abstract excerpt

Recent advances in sequencing technologies have enabled us to scrutinize the versatile underlying mechanisms of cancer more precisely. However, adopting these new sophisticated technologies is challenging for clinical labs as it involves complex workflows, and requires validation for diagnostic purposes. The aim of this work is towards the analytical validation of a next generation sequencing (NGS) panel for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Mutational Analysis
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 28049581
DOI: 10.1016/j.prp.2016.11.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Validation of a next generation sequencing panel for detection of hotspot cancer mutations in a clinical laboratory.PMID 28049581Read ↗

Use of the Ion AmpliSeq Cancer Hotspot Panel in clinical molecular pathology laboratories for analysis of solid tumours: With emphasis on validation with relevant single molecular pathology tests and the Oncomine Focus Assay.Semantic proximity Read ↗

Validation of the Oncomine™ focus panel for next-generation sequencing of clinical tumour samples.Semantic proximity Read ↗

Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.Semantic proximity Read ↗

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.Semantic proximity Read ↗

Validation of a next-generation sequencing assay for clinical molecular oncology.Semantic proximity Read ↗

Quality control material for the detection of somatic mutations in fixed clinical specimens by next-generation sequencing.Semantic proximity Read ↗

Routine use of the Ion Torrent AmpliSeq™ Cancer Hotspot Panel for identification of clinically actionable somatic mutations.Semantic proximity Read ↗

Validation and Implementation of a Custom Next-Generation Sequencing Clinical Assay for Hematologic Malignancies.Semantic proximity Read ↗

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.Semantic proximity Read ↗

Single-Center Experience with a Targeted Next Generation Sequencing Assay for Assessment of Relevant Somatic Alterations in Solid Tumors.Semantic proximity Read ↗

Development and validation of an ultra-high sensitive next-generation sequencing assay for molecular diagnosis of clinical oncology.Semantic proximity Read ↗

Germline and somatic mutation profile in Cancer patients revealed by a medium-sized pan-Cancer panel.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.