Article
Quality control material for the detection of somatic mutations in fixed clinical specimens by next-generation sequencing.
Diagnostic pathology - 17 Sept 2015
Dumur Catherine I, Almenara Jorge A, Powers Celeste N, Ferreira-Gonzalez Andrea
Abstract excerpt
BACKGROUND: Targeted next generation sequencing (NGS) technology to assess the mutational status of multiple genes on formalin-fixed, paraffin embedded (FFPE) tumors is rapidly being adopted in clinical settings, where quality control (QC) practices are required. Establishing reliable FFPE QC materials for NGS can be challenging and/or expensive. Here, we established a reliable and cost-effective FFPE QC material...
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