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Development and validation of an ultra-high sensitive next-generation sequencing assay for molecular diagnosis of clinical oncology.

International journal of oncology - 1 Nov 2016

Liang Jiao, She Yaoguang, Zhu Jiaqi, Wei Longgang, Zhang Lanying, Gao Lianju, Wang Yan, Xing Jing, Guo Yang, Meng Xuehong, Li Peiyu

Abstract excerpt

Dramatic improvements in the understanding of oncogenes have spurred the development of molecular target therapies, which created an exigent need for comprehensive and rapid clinical genotyping. Next-generation sequencing (NGS) assay with increased performance and decreased cost is becoming more widely used in clinical diagnosis. However, the optimization and validation of NGS assay remain a challenge, especially...

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PMID: 27826616
DOI: 10.3892/ijo.2016.3707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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