Article
The rs7044343 Polymorphism of the Interleukin 33 Gene Is Associated with Decreased Risk of Developing Premature Coronary Artery Disease and Central Obesity, and Could Be Involved in Regulating the Production of IL-33.
PloS one - 1 Jan 2017
Angeles-Martínez Javier, Posadas-Sánchez Rosalinda, Llorente Luis, Alvarez-León Edith, Ramírez-Bello Julian, Villarreal-Molina Teresa, Lima Guadalupe, Cardoso-Saldaña Guillermo, Rodríguez-Pérez José Manuel, Pérez-Hernández Nonanzit, Fragoso José Manuel, Posadas-Romero Carlos, Vargas-Alarcón Gilberto
Abstract excerpt
AIM: The effect of interleukin 33 (IL-33) in the inflammatory process generates significant interest in the potential significance of IL-33 as a biomarker for coronary artery disease (CAD). Here, our objective was to analyze whether IL-33 gene polymorphisms are associated with premature CAD in a case-control association study. METHODS: Four IL-33 polymorphisms (rs7848215, rs16924144, rs16924159 and rs7044343)...