Article
Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study.
Mediators of inflammation - 1 Jan 2017
Posadas-Sánchez Rosalinda, Pérez-Hernández Nonanzit, Angeles-Martínez Javier, López-Bautista Fabiola, Villarreal-Molina Teresa, Rodríguez-Pérez José Manuel, Fragoso José Manuel, Posadas-Romero Carlos, Vargas-Alarcón Gilberto
Abstract excerpt
Interleukin 35 (IL-35) is a heterodimeric cytokine involved in the development of atherosclerosis. The aim of the present study was to establish if the polymorphisms of IL-12A and EBI3 genes that encode the IL-35 subunits are associated with the development of premature coronary artery disease (CAD) in Mexican individuals. The IL-12A and EBI3 polymorphisms were determined in 1162 patients with premature CAD and...
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