Article
Associations between variants in IL-33/ST2 signaling pathway genes and coronary heart disease risk.
International journal of molecular sciences - 15 Dec 2014
Wu Fangqin, He Mei'an, Wen Qiang, Zhang Wencai, Yang Jinhua, Zhang Xiaomin, Wu Tangchun, Cheng Longxian
Abstract excerpt
The IL-33/ST2 signaling pathway plays an important role in coronary artery disease (CHD); however, few studies have explored how variants in IL-33/ST2 genes influence CHD risk. Here, we examined the association between genetic variants in IL-33, ST2, and IL-1RAcP of the IL-33/ST2 axis and the risk of CHD. We conducted a case-controlled study with 1146 CHD cases and 1146 age- and sex-frequency-matched controls....
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